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NYU College of Dentistry and Bluestone Center Investigators Publish in Journal of Periodontology

August 16, 2013

Investigators found that maxillary sinus membrane perforation, a complication of the maxillary sinus augmentation procedure, is not an adverse complication when properly restored during surgery.

Researchers from the New York University College of Dentistry (NYUCD) and the Bluestone Center for Clinical Research have published an article based on these findings, “Effect of Maxillary Sinus Membrane Perforation on Vital Bone Formation and Implant Survival: A Retrospective Study” (http://www.joponline.org/doi/abs/10.1902/jop.2012.120458), in the August 2013 issue of the Journal of Periodontology

The article was coauthored by Stuart J. Froum, DDS, clinical professor and director of clinical research in the Ashman Department of Periodontology and Implant Dentistry; Ismael Khouly, DDS, MS, clinical assistant professor of oral and maxillofacial surgery and clinical research coordinator at the  Bluestone Center for Clinical Research; Sang-Choon Cho, DDS, MS, clinical assistant professor and director of the Advanced Program in Implant Dentistry for International Dentists;and Giovanni Favero, DDS, University of Padua, Italy. Maxillary sinus augmentation (MAP) is often performed to increase the amount of bone in the posterior maxilla, or upper jaw bone, prior to the placement of an implant. Using the lateral window technique, MAP is generally considered to be safe with a low incidence of complications. However, one of the most frequent intraoperative complications of the technique is maxillary sinus membrane perforation (MSMP).

A successful MAP is often defined by the amount of vital bone formation following graft maturation and the long-term survival rate of the implants placed into that bone. Therefore, the authors examined the effect of MSMP on vital bone formation and implant survival.

The authors performed a retrospective study (1998-2008) of a total of 23 patients who had received bilateral sinus augmentation using the lateral wall technique. To determine the amount of vital bone, masked histomorphometric analysis was performed by independent examiners at the Hard Tissue Research Laboratory at the University of Minnesota. Implant survival following placement was reported from 6 to 32 months.

While there was no statistically significant difference in implant failure, the authors found there was a significant increase in vital bone percentage in perforated sinuses (26.3% ± 6.3%) compared to non-perforated sinuses (19.1% ± 13.7%). These findings indicate sinus MSMPs, when properly repaired during surgery, do not appear to be an adverse complication with respect to implant survival or vital bone production. 

About the Bluestone Center for Clinical Research: The Bluestone Center for Clinical Research, in conjunction with the NYU Oral Cancer Center, is an academic research organization located at the NYU College of Dentistry. Bluestone’s mission is to take a creative scientific approach to transform world health. Bluestone is dedicated to conducting research in oral cancer, cancer symptomology, pharmaceuticals, medical devices, emerging biotechnology, periodontics, implants, and oral health products. Press contact: Andrea Flynn, AndreaN.Flynn@nyu.edu, 212-998-9892.