Bluestone's Expertise

At Bluestone, we conduct phase 1 through phase 4 clinical trials in dental and medical research with a focus on oral health.

Clinical trials open for enrollment

For a list of clinical trials currently open for recruitment, click here.

Ongoing clinical trials (closed for enrollment)

Keratocystic Odontogenic Tumor (KCOT) Study

Status: Ongoing, enrollment of subjects completed.

Continue ...

Study duration: 3 years
Required visits: up to 20 visits
Age of participants: 18 or older years
Gender of participants: male and female

 

Completed clinical trials

Dry Mouth Study

Status: Completed.

The purpose of this study is to test how well 2 new mouth rinses relieve dry mouth. Continue ...

Study duration: 6 weeks
Required visits: 7
Age of participants: 18-70 years
Gender of participants: male and female

 

Tooth Whitening Study

Status: Completed.

PLEASE NOTE: We can no longer accept new participants for this studyThe purpose of the study is to collect data to allow the development of a device that measures tooth color. The study will test three different methods of measuring tooth color. Continue ...

Study duration: approximately 4 weeks
Required visits: 4
Age of participants: 21-60 years
Gender of participants: male and female

 

Cancer Pain Study

Status: Completed.

Battling cancer is its own challenge. But when youre also fighting the chronic or continuing pain associated with cancer, this challenge can be overwhelming. Doctors typically prescribe medicationssuch as morphine or oxycodonefor chronic cancer pain relief; however, even with increased medication dosage, some patients still experience chronic pain. Continue ...

Study duration: 9 weeks
Required visits: 4
Age of participants: 18 yrs and older years
Gender of participants: male and female

 

Mouthwash Study

Status: Completed.

The Bluestone Center for Clinical Research is seeking volunteers to take part in a clinical research study. The purpose of this study is to find out the effects of three differentdoses of a mouthwash,and how effectively the mouthwash killsbacteria present in the mouth. Tooth decay is the process that results in a cavity (dental caries). Continue ...

Study duration: 6 Months
Required visits: 10
Age of participants: 18-older years
Gender of participants: male and female

 

Do you have Gum Disease?

Status: Completed.

PLEASE NOTE: We can no longer accept new participants for this study.If you are at least 25 years of age, have at least 20 natural teeth, have gum disease, have not used tobacco products for at least a year, you may qualify to participate in a research study at the NYU Bluestone Center for Clinical Research. Continue ...

Study duration: Approx. 21 month
Required visits: 14
Age of participants: 25+ years
Gender of participants: male and female

 

Symptoms Related to Chemotherapy Study

Status: Completed.

The Bluestone Center for Clinical Research and the NYU Langone Medical Center, funded by the National Cancer Institute are seeking volunteers to take part in a clinical research study. The purpose of this study is to better understand how symptoms (i.e. Continue ...

Study duration: 4-8 weeks
Required visits: 2
Age of participants: 18+ years
Gender of participants: male and female

 

Dental Implant Study

Status: Completed.

PLEASE NOTE: We can no longer accept new participants for this study.The propose of this study is to evaluate bone and gum dimension changes around implants placed in different position into the bone. Continue ...

Study duration: 24 up to 30 months
Required visits: 9-10
Age of participants: 18-older years
Gender of participants: male and female

 

Oral Precancer and Cancer Study

Status: Completed.

The Bluestone Center for Clinical Research is seeking volunteers to take part in a clinical research study. The purpose of this study is to develop a new test that will help with early detection of oral cancer and precancerous changes of the mouth.Study Details:Oral cancer is a global health problem afflicting close to 300,000 people each year. Continue ...

Study duration: 1 hour
Required visits: 1
Age of participants: 18 and older years
Gender of participants: male and female

 

Women and Facial Pain Study

Status: Completed.

The purpose of this study is to better understand the underlying causes of facial pain involving the chewing muscles, by comparing sleep behavior and other nervous system patterns of women with and without chronic facial pain. Continue ...

Study duration: 1 week
Required visits: 3 (two overnight)
Age of participants: 18-80 years old years
Gender of participants: female

 

HIV Research Study

Status: Completed.

PLEASE NOTE: We can no longer accept new participants for this study.The purpose of this study is to examine HIV's effect on the digestive tract and the mouth.This study will examine the changes that occur in the mouth which are related to the treatment of HIV disease.In order to examine these changes we need participants who are HIV-positive. Continue ...

Study duration: 6 months to 2 years
Required visits: 3-10
Age of participants: 18 and over years
Gender of participants: male and female

 

Dental Remineralization Study

Status: Completed.

If you are between 18-70 years of age and are in good general health you may be eligible to participate in a research study at the Bluestone Center for Clinical Research. The study consists of 6 visits over a period of approximately a month. Continue ...

Study duration: 30 days
Required visits: 5
Age of participants: 18-70 years old years
Gender of participants: male and female

 

Pharyngitis (Sore Throat) Study

Status: Completed.

We are conducting a study in orderto gather more information on the safety of flurbiprofen 8.75 mg lozenge and how well the lozenge works against sore throat pain. The study consists of 3 visits over 7 to 10 days. Continue ...

Study duration: 2
Required visits: 3
Age of participants: Over 18 years years
Gender of participants: male and female

 

Oral Leukoplakia

Status: Completed.

The purpose of this study is to evaluate how a product made from soybeans named Bowman-Birk Inhibitor Concentrate (BBIC) affects white or red patches in your mouth (oral leukoplakia).BBIC is derived from soybeans and belongs to a class of compounds known as protease-inhibitors. Continue ...

Study duration: 32
Required visits: 6
Age of participants: 18 or older years
Gender of participants: male and female

 

Psoriasis Study

Status: Completed.

We are conducting a clinical trial for an investigational medication for the treatment of moderate to severe psoriasis. The purpose of this study is to determine the safety of novel treatment and to learn about how it interacts with the body in people with moderate to severe psoriasis. Continue ...

Study duration: 22
Required visits: 19
Age of participants: 18 or older years
Gender of participants: male and female

 

Single posterior (back) dental implant

Status: Completed.

Interested subjects are being asked to participate in this study because they need to have a single posterior (back) dental implant placed. Continue ...

Study duration: 16
Required visits: 6
Age of participants: Over 18 years
Gender of participants: male and female

 

NYU Cancer Anxiety Study

Status: Completed.

PLEASE NOTE:We can no longer accept new participants for this study. Continue ...

Study duration: 36 weeks
Required visits: Several
Age of participants: 18-76 years
Gender of participants: male and female

 

Mouthwash study

Status: Completed.

Continue ...

Study duration: 12
Required visits: 3
Age of participants: 18 - over years
Gender of participants: male and female

 

Sinus lift study

Status: Completed.

If you desire dental implants, but do not have sufficient bone for the procedure, you may be eligible to participate in this research study at no cost to you. The purpose of this study is to compare the effectiveness of two materials for producing vital bone 4 to 5 months following sinus graft surgery. Continue ...

Study duration: 32
Required visits: 6-11
Age of participants: Over 18 years
Gender of participants: male and female

 

Sinus Lift Study

Status: Completed.

If you desire dental implants, but do not have sufficient bone for the procedure, you may be eligible to participate in this research study at no cost to you.The purpose of this study is to compare the effectiveness of two materials for producing vital bone four to five months following sinus graft surgery. Continue ...

Study duration: 32
Required visits: 6-11
Age of participants: Over 18 years
Gender of participants: male and female

 

Dental Restoration (Tooth Filling) Study

Status: Completed.

Interested subjects are being asked to participate in this study because they have a need to have two fillings placed or restored.This research study is comparing 2 different bonding materials that hold the dental restoration (filling) in place. Continue ...

Study duration: 7
Required visits: 5
Age of participants: Over 18 years
Gender of participants: male and female

 

Dry Mouth Study

Status: Completed.

We are conducting a clinical trial to test a new treatment for the relief of dry mouth symptoms.The purpose of this study is to test how well an over the counter adhesive disc placed inside your mouth works to help relieve dry mouth symptoms and freshen breath. Continue ...

Study duration: 5
Required visits: Approximately 6
Age of participants: 18 - 90 years
Gender of participants: male and female

 

Facial Pain Study (Botox)

Status: Completed.

If you are at least 18 years of age old and suffer from facial pain (trigeminal neuralgia), you may be eligible to participate in a research study at the NYU Bluestone Center for Clinical Research.Study Details:This study consists of 6-10 visits to our study site, over a 12 to 20 week period with three follow-up phone calls. Continue ...

Study duration: 21
Required visits: 6 - 10
Age of participants: 18 - 70 years years
Gender of participants: male and female

 

Sjogren's Syndrome Study

Status: Completed.

If you are at least 18 years of age and interested in gaining more knowledge of Sjogrens Syndrome (an autoimmune disease), you may be eligible to participate in this study.Study Details:Interested participants should be diagnosed with Sjogrens Syndrome prior to participation in this study. Continue ...

Study duration: 21
Required visits: 1
Age of participants: 18 - 65 years years
Gender of participants: male and female

 

HIV Associated Oral Warts Study

Status: Completed.

If you suffer from multiple oral warts associated with HIV infection and are 18 years of age or older, you may qualify to participate in a research study being conducted at the NYU Bluestone Center for Clinical Research. Continue ...

Study duration: 21
Required visits: 6
Age of participants: 18 - 65 years years
Gender of participants: male and female

 

Oral Cancer Detection Study

Status: Completed.

If you are a heavy smoker or drinker and you are at least 45 years of age, you may qualify to participate in a clinical research study being conducted at the NYU Bluestone Center for Clinical Research.Study Details:Your participation will involve one to three visits, which will take place over approximately three weeks. Continue ...

Study duration: 21
Required visits: 1-3 visits (depending on screening diagnosis)
Age of participants: 45 and older years
Gender of participants: male and female

 

Dental Restoration (Crown/Filling) Study

Status: Completed.

If you are at least 18 years of age and need a crown or filling on one or more of your tooth/teeth, you may qualify to participate in a research study at the NYU Bluestone Center for Clinical Research.Study Details:This study consists of three visits to our study site, over a three-month period. Continue ...

Study duration: 52
Required visits: 3
Age of participants: 18 - 65 years years
Gender of participants: male and female

 

Cancer Pain Study

Status: Completed.

To be eligible for this study, you must be at least 17 years of age and regularly experiencingat least one but no more than four episodes of breakthrough pain per day.Study Details:This study consists of 18 visits to our study site, over a 13-month period. Qualified participants will be compensated for time and travel expenses. Continue ...

Study duration: 21
Required visits: 18
Age of participants: 17 - 75 years years
Gender of participants: male and female

 

HIV-Associated Diarrhea Study

Status: Completed.

We are testing an investigational medicine that may help control HIV-associated diarrhea. You have to be at least 18 years of age and HIV-positive in addition to other eligibility criteria to participate in this study. Study Details:At the first visit of this study, the doctor will make sure you are eligible to participate. Continue ...

Study duration: 21
Required visits: 9
Age of participants: 18 - 75 years years
Gender of participants: male and female

 

Lupus Study

Status: Completed.

If you are at least 18 years of age and suffer from systematic lupus, then you may qualify to participate in a research study at the NYU Bluestone Center for Clinical Research. Continue ...

Study duration: 21
Required visits: 10-13
Age of participants: 18 - 75 years years
Gender of participants: male and female

 

Tooth Sensitivity Study

Status: Completed.

If you are at least 18 years of age and suffer from sensitive teeth, then you may qualify to participate in a research study at the NYU Bluestone Center for Clinical Research.Study Details:This study consists of four visits to our study site, over an eight-week period. Qualifying participants can be compensated for time and travel expenses. Continue ...

Study duration: 8
Required visits: 4
Age of participants: 18 - 75 years years
Gender of participants: male and female

 

Nighttime Heartburn Study

Status: Completed.

If you are at least 18 years of age and experienced nighttime heartburn at least two days and nights per week over the past month, you may qualify to participate in a research study at the NYU Bluestone Center for Clinical Research aimed at helping individuals who suffer with nighttime heartburn. Continue ...

Study duration: 21
Required visits: 5
Age of participants: 18 - 75 years years
Gender of participants: male and female