Bluestone Trials

Women and Facial Pain Study

Facial Pain causing you discomfort?
Status: Completed.

The purpose of this study is to better understand the underlying causes of facial pain involving the chewing muscles, by comparing sleep behavior and other nervous system patterns of women with and without chronic facial pain. 

If you are a woman who is at least 18 years of age and suffer from a TMJ problem, involving pain or ache in the chewing muscles of your face, then you may qualify to participate in a research study at the NYU Bluestone Center for Clinical Research.

This TMJ study conducted at the NYU Bluestone Center for Clinical Research requires that interested participants must be diagnosed by with a muscle-pain-based TMJ problem by NYU Bluestone research investigators, meet other study criteria, and be willing to comply with study procedures and required study participation visits to be eligible to participate in this study.

This study consists of 3 visits: the first will be a four-hour daytime study at our study site and the 2nd and 3rd visits will involve consecutive overnight stays at an NYU-affiliated sleep lab in Manhattan. All study visits will be completed within one week. Participants will be compensated for time and travel expenses, if they qualify. 

Study Background:

Muscle-based TMJ problems involve pain or ache in the chewing muscles of the face. Their cause is a matter of scientific controversy. This study is not a treatment study, but is designed to help doctors and scientists understand the possible causes of muscle-based TMJ. Some doctors think that they are caused by grinding and clenching of the teeth, especially at night. Some doctors think that they are caused by how the central nervous system (brain and spinal cord) processes painful sensations. By studying facial muscle activity during sleep and during the day, as well as studying how the nervous system of people with TMJ pain respond when patients feel warm-to-hot surfaces, this study will help to identify the cause of muscle-based TMJ problems.