Seeking patients to test a mouthwash intended to prevent tooth decay (cavity)
The Bluestone Center for Clinical Research is seeking volunteers to take part in a clinical research study. The purpose of this study is to find out the effects of three different doses of a mouthwash, and how effectively the mouthwash kills bacteria present in the mouth.
Tooth decay is the process that results in a cavity (dental caries). It occurs when bacteria in your mouth make acids that break down the surface of your tooth causing a cavity. Tooth decay is an infectious disease and may be caused by a combination of multiple factors such as microbial colonization, poor oral hygiene or genetic predisposition, among others.
This study will be testing a new drug which has been approved by the U.S. Food and Drug Administration (FDA) for testing. Previous studies performed with this drug demonstrated activity selectively targeting Streptococcus mutans, a cavity-causing organism.
Participants must be at least 18 years of age and have had dental cavities in the past. Participation will involve 10 visits over a 6-month period. Most visits will last approximately 1 to 3 hours, and one visit will last 9 hours. If eligible, you will receive a free dental cleaning and compensation for your time and travel. Confidentiality will be maintained for all participants.